Read answers to frequently asked questions
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Side Effect Management
VIJOICE® (alpelisib) tablets
What are some tips for managing certain side effects?
Below are some suggestions that your doctor may offer to help you manage some of the most common side effects of VIJOICE® (alpelisib) tablets. Always talk to your doctor before making any changes to your diet or exercise routine.
Hyperglycemia, or high blood sugar
Hyperglycemia may occur when taking VIJOICE. It’s important to understand the difference between hyperglycemia and diabetes.
- Hyperglycemia is high blood sugar due to any cause and also is a characteristic of diabetes
- Type 1 diabetes is a condition in which your body stops making the insulin it needs to let blood sugar enter the cells of the body
- Type 2 diabetes is a condition in which your body either doesn’t make enough insulin or is unable to use it correctly
If you have a history of diabetes, talk to your doctor about how that might affect treatment with VIJOICE. In general, hyperglycemia that can be caused by VIJOICE is not diabetes.
If you experience hyperglycemia, your doctor may prescribe a medication (such as metformin), along with suggested lifestyle changes, and may require dose interruption, reduction, or discontinuation based on the severity of hyperglycemia.
Signs of hyperglycemia include:
- excessive thirst
- dry mouth
- more frequent urination than usual or a higher amount of urine than normal
- increased appetite with weight loss
- fruity odor on breath
- difficulty breathing
- dry or flushed skin
Contact your doctor immediately if you experience any signs and features of hyperglycemia. Your doctor may require dose interruption, reduction, or discontinuation based on the severity of hyperglycemia.
Stomatitis, or mouth sores
Stomatitis is common with VIJOICE. Follow your doctor’s instructions for how to manage stomatitis.
Diarrhea or colitis, or inflammation of your intestines
Diarrhea is common with VIJOICE and may be severe. Follow your doctor’s instructions for how to manage diarrhea or colitis.
- Your doctor may tell you to drink more fluids or take medicines (like an antidiarrheal) to treat diarrhea or colitis
- Talk to your doctor if antidiarrheal medicine does not help with your diarrhea or colitis
- If you have diarrhea or colitis, your doctor may need to interrupt, reduce your dose of, or discontinue VIJOICE
You can help manage diarrhea or colitis by watching what you eat and drink